‪Assistant Professor of Pediatrics, Stanford University‬ - ‪‪Cited by 2,461‬‬ - ‪Neurodevelopment‬ - ‪Brain injury of prematurity‬ Pasca Lab @ Stanford University - Home. Ono T, Takeshita A, Kishimoto Y, et al. Blood. Sergiu Pasca, 1, † Ciprian Tomuleasa . 2016;101(9):e385-e386386. Colorectal cancer (CRC) is the 3 rd most common cancer and the 2 nd leading cause of cancer-related death worldwide, according to WHO data in 2019. by | Jan 20, 2022 | dwyer high school basketball state championship | typecast will you ever learn | Jan 20, 2022 | dwyer high school basketball state championship | typecast will you ever learn No man-made device of any kind, computer or otherwise, has yet come close to displaying anything like artificial intelligence on the human level. Runt (Runt domain)‐related transcription factor 1 (RUNX1) is a transcription factor belonging to the core‐binding factor (CBF) family. PubMed Article Google Scholar 3. 21. Previous to Sergiu's current city of Menlo Park, CA, Sergiu Pasca lived in Palo Alto CA. At an age when most children want to play sports or hang out with friends, Pasca's chosen pastime looked a lot like work — but Pasca could hardly tell the difference. Hydrogen gas has been reported to have medical efficacy since the 1880s. However, the identification of metastatic carcinoma cells on bone marrow aspiration smears is technically . Understanding spinal cord generation and assembly is essential to elucidate how motor behavior is controlled and how disorders arise. Consequently, the anatomical and functional basis of gut-to-brain circuitry dysfunction in PD—such as network activity and dopamine signaling—remain poorly understood. Correction 04 November 2020: An earlier version of this story misrepresented the position of Sergiu Pasca. Alfredo M. Valencia is part of Stanford Profiles, official site for faculty, postdocs, students and staff information (Expertise, Bio, Research, Publications, and more). Several positions available in the lab. Ina Anreiter. Mitsunaga T., Hasegawa I., Uzura M., Okuno K., Otani K., Ohtaki Y., Sekine A., Takeda S. Comparison of the National Early Warning Score (NEWS) and the Modified Early Warning Score (MEWS) for predicting admission and in-hospital mortality in elderly patients in the pre-hospital setting and in the emergency . . The aim of this systematic review and meta-analysis was to analyze the available evidence on the assessment of periodontal disease in patients with von Willebrand disease (VWD). Europe PMC is an archive of life sciences journal literature. Histology and Histopathology 2021-2022 IF 임팩트 팩터는 2.303입니다. Sergiu Pasca is a fellow of Stanford ChEM-H. Scientists from Seoul National University and the University of California-San Francisco also contributed to the research. CAS Article Google Scholar Download references. She studied at the University Lisbon and the University of Toronto, where she earned a PhD in Ecology and Evolutionary Biology. At about the same time that Lancaster was working with cerebral organoids in Vienna, Sergiu Pasca at Stanford University was trying to find a way to keep cells alive in vitro for long enough to be able to capture the incredibly long process of human corticogenesis and to study the mechanisms underlying neurodevelopmental disorders such as . More about Sergiu in this SFARI Rising Star profile, the Stanford Medicine Magazine story and the Vilcek award profile and story or the Nature Medicine profile, The Scientist: Brain Builder . Laura Roberts, MD, MA Katharine Dexter McCormick and Stanley McCormick Memorial Professor in the School of Medicine and Professor, by courtesy, of Psychology. Andrei Colita 1,2 †, Anca Colita 3,4 †, Horia Bumbea 1,5 †, Adina Croitoru 4 †, Carmen Orban 4 †, Lavinia Eugenia Lipan 4, Oana-Gabriela Craciun 4, Dan Soare 1,5, Cecilia Ghimici 1,2, Raluca Manolache 1,2, Ionel Gelatu 1,2, Ana-Maria Vladareanu 1, Sergiu Pasca 6,7, Patric Teodorescu 7,8, Delia Dima 7, Anca Lupu 1,2, Daniel Coriu 1,9, Ciprian Tomuleasa 6,7 * and Alina Tanase 4 The diagnosis is critical for tumor staging, treatment selection and prognostic risk stratification. Ancuta Jurj, Laura Pop, Bobe Petrushev, Sergiu Pasca, Delia Dima, Ioana Frinc, Dalma Deak, Minodora Desmirean, Adrian Trifa, Bogdan Fetica, Grigore Gafencu, Sonia Selicean, Vlad Moisoiu, Wilhelm-Thomas Micu, Cristian Berce, Alexandra Sacu, Alin Moldovan, Andrei Colita, Horia Bumbea, Alina Tanase, Angela Dascalescu, Mihnea Zdrenghea, Rares . 1. Correction 04 November 2020: An earlier version of this story misrepresented the position of Sergiu Pasca. 2019. Panagiotakos and Pasca highlight mechanisms conferring unique developmental roles to disease-associated ion channels and synaptic proteins, arguing that incorporating spatiotemporally distinct and cell-type-specific functions is essential for our emerging framework for understanding neuropsychiatric disorders. Verified email at cs.ubbcluj.ro - Homepage. In the past two decades, more than 1000 papers . T cells can turn back cancer, but they don't always reach tumor cells in sufficient numbers to do so. 2021. Sergiu Pasca a plecat din Romania in 2009 si la doar 31 de ani a reusit sa detina propriul laborator la una dintre cele mai mari si mai importante universitati din SUA. Ordinary Differential Equations Partial Differential Equations Nonlinear Dynamics Mathematical Modelling. Background: Hepatic hydrothorax (HH) is an understudied complication of decompensated cirrhosis. Expression of CD56 is an unfavorable prognostic factor for acute promyelocytic leukemia with higher initial white blood cell counts. Sergiu receives the 2022 IBRO-Kemali Prize in Neuroscience [ press release] New paper published in Cell. The award-winning documentary Minds Wide Open featuring our research . Sergiu Pasca are 39 de ani si este profesor asistent de psihiatrie si stiinte comportamentale la Universitatea Stanford.Sergiu Pasca a plecat din Romania in 2009 si la doar 31 de ani a reusit sa detina propriul laborator la una dintre cele mai mari si mai importante . Incepand din ianuarie 2014, doctorul Sergiu Pasca conduce propriul sau grup de cercetare in calitate de membru al corpului profesoral al Universitatii Stanford in California. Lorand Gabriel Parajdi. Tânărul om de știință român Sergiu Paşca, profesor asistent de psihiatrie şi ştiinţe comportamentale la Universitatea Stanford din SUA, a obţinut un premiu important ca urmare a cercetărilor sale avansate în domeniul tratării bolilor neuropsihice. TET2 is a dioxygenase dependent on Fe2+ and α-ketoglutarate which oxidizes 5-methylcytosine (5meC) to 5-hydroxymethylcytosine (5hmeC). Google Scholar). Sergiu P Paşca The construction of the human nervous system is a distinctly complex although highly regulated process. Constantinescu, Catalin, Sergiu Pasca, Sabina Iluta, Grigore Gafencu, Maria Santa, Ciprian Jitaru, Patric Teodorescu, Delia Dima, Mihnea Zdrenghea, and Ciprian Tomuleasa. "The Predictive Role of Modified Early Warning Score in 174 Hematological Patients at the Point of Transfer to the Intensive Care Unit" Journal of Clinical Medicine 10 . As part of the Aligning Science Across Parkinson's (ASAP) initiative, our team is characterizing circuit mechanisms underlying gut-to-brain disease spread and progression . PubMed Article Google Scholar 3. Blood 2011; 118:4880 10.1182/blood.V118.21.4880.4880 [Google Scholar] 189. Studies considered eligible for . Nor has any device . PubMed CrossRef Google Scholar 36. Sergiu Paşca illustrates how emerging three-dimensional culture methods enable differentiated human stem cells to form into brain organoids or . LAB NEWS: The assembloids pioneered by our lab featured in Nature. Article Google Scholar 5. We aimed to evaluate the long-term prognosis of patients with HH by comparing them with a matched non-HH group. The cellular landscape of the human spinal cord remains, however, insufficiently explored. (2014) 92:CD009411 10.1016/j.critrevonc.2014.04.003 [Google Scholar] 23. Mulligan G, Lichter DI, Di Bacco A, Blakemore SJ, Berger A, Koenig E, et al. IntroductionMetastatic carcinomas of bone marrow (MCBM) are characterized as tumors of non-hematopoietic origin spreading to the bone marrow through blood or lymphatic circulation. The two blood tumor entities were clonally unrelated. Haematologica. Moreover, as studies advance, a clearer . In 2019-20 she was a Schmidt Science Fellow . Sergiu P. Pasca is the recipient of the 2018 Vilcek Prize for Creative Promise in Biomedical Science.Sergiu Pasca explores the biological underpinnings of br. ปัจจัยกระทบ 2021-2022 ของ Frontiers in Oncology คือ 6.244 ปัจจัยกระทบ การวิเคราะห์, แนวโน้ม, การจัดอันดับ & คาดการณ์. The site facilitates research and collaboration in academic endeavors. Frontiers in Oncology 2021-2022 IF 임팩트 팩터는 6.244입니다. The project was by enlarged funded by K08 HL127269 (GG), R03 HL145226 (GG), P01CA225618 (BDS, RJJ, GG), and LLS TRP 14086277 (RJJ . Valmu L, Alfthan H, Hotakainen K, Birken S, Stenman U-H. Site-specific glycan analysis of human chorionic gonadotropin -subunit from malignancies and pregnancy by liquid chromatography—electrospray mass spectrometry. Pașca is a faculty member in the Department of Psychiatry and Behavioral Sciences at Stanford University, a neuroscientist and stem cell biologist and currently a NYSCF Robertson Investigator. An electronic search in three databases (PubMed, Web of Science, and Scopus) was conducted by three independent reviewers to identify cross-sectional, cohort, and clinical trial studies. [Google Scholar] 4. Romania is a region with high . Post published: October 13, 2020. Monti, M. M. et al. Hydrogen gas is the simplest molecule in nature which is formed by two hydrogen atoms. Recent research, both basic and clinical, has proven that hydrogen is an important physiological regulatory factor with antioxidative, anti-inflammatory, and antiapoptotic effects. Zinzani PL, Pellegrini C, Argnani L, Broccoli A. [PMC free article] [Google Scholar] 11. Human tissue inaccessibility has impeded a molecular understanding of the. Considering the dismal prognosis this disease presents, several efforts have been made to better classify it and offer a tailored treatment to each subtype. Among these oxidized methylcytosines, 5fC and 5caC are directly excised by thymine DNA glycosylase (TDG) and ultimately . . Introduction. Societatea Internaţională de Cercetare în domeniul Schizofreniei (SIRS) l-a numit pe Sergiu Paşca, cercetătorul anului 2021. ‪Associate Professor, Stanford University‬ - ‪‪5.094 citazioni‬‬ - ‪Neuroscience‬ - ‪Stem Cells‬ - ‪Organoids & Assembloids‬ - ‪Molecular Biology‬ - ‪Psychiatry‬ Search life-sciences literature (Over 39 million articles, preprints and more) A close look at the cells of tumor blood vessels suggests a way to boost T cell migration in . Read Full Summary Apply here (LSRP-1), here (LSRP-2) and here (LSRP-3). Un medic roman originar din Aiud face istorie in SUA in domeniul cercetarilor dedicate tratarii bolilor neuropsihice. Rancea M, Monsef I, von Tresckow B, Engert A, Skoetz N. High-dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin lymphoma . Acute myeloid leukemia (AML) is a hematologic malignancy characterized by abnormal proliferation and a lack of differentiation of myeloid blasts. Still, medical researchers did not pay much attention to hydrogen gas until the 20th century. (2014) 92:CD009411 10.1016/j.critrevonc.2014.04.003 [Google Scholar] 23. Candidate papers were limited to English, German, and French language publications, but were not limited to any geographical region, and the most recent search was performed on . The studies included in the present analysis were identified after a search of the National Library of Medicine's MEDLINE database using PubMed and Google Scholar. N . Sergiu Pasca set up his first science lab at the age of 11, in the basement of his parents' 150-year-old house in Aiud, Romania. Methods: This retrospective study included 763 consecutive patients hospitalized for decompensated cirrhosis and ascites. Sergiu Pasca Stanford University, United States. Organoids of intelligence. BCR-ABL1 IS in the Avant-Garde of Molecular Hematology, Frontiers in Oncology, 10.3389/fonc.2019.00863, 9, (2019). Vlad Moisoiu, Patric Teodorescu, Lorand Parajdi, Sergiu Pasca, Mihnea Zdrenghea, Delia Dima, Radu Precup, Ciprian Tomuleasa, Simona Soverini, Assessing Measurable Residual Disease in Chronic Myeloid Leukemia. Welcome to the lab for Integrative Cellular Biology and Bioformatics at Saarland University headed by junior professor Dr. Fabian Müller. Among these oxidized methylcytosines, 5fC and 5caC are directly excised by thymine DNA glycosylase (TDG) and ultimately . Faculty Host: Tom Clandinin. Articles Cited by Co-authors. A 57-year-old man affected by high-risk progressive chronic lymphocytic leukemia (CLL), primary resistant to first-line chemoimmunotherapy, developed a type A lymphomatoid papulosis (LyP) during a second progression of CLL. CAS Article Google Scholar 4. This has been formally done by the World Health Organization (WHO) with the AML . Faculty of Mathematics and Computer Science, Babeș-Bolyai University. ObjectiveTo explore the role of chidamide, decitabine plus priming regimen in the salvage treatment of relapsed/refractory acute myeloid leukemia.MethodsA clinical trial was conducted in relapsed/refractory acute myeloid leukemia patients using chidamide, decitabine, cytarabine, idarubicin, and granulocyte-colony stimulating factor, termed CDIAG, a double epigenetic priming regimen . Ο Δείκτης απήχησης 2021-2022 του Histology and Histopathology είναι 2.303 Δείκτης απήχησης Ανάλυση, Τάση, Σειρά κατάταξης & Προφητεία. TET proteins successively oxidize 5mC to yield 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). One of these multi-dimensional factors, which has gained increased attention in the oncological field due to its unelucidated role in risk assessment for cancer, is diet. Prolonged disease-free survival in elderly relapsed diffuse large B-cell lymphoma patients treated with lenalidomide plus rituximab. DC generation and confirmation of DC product. Furthermore, the incidence of CRC in individuals younger than 50 years of age has increased (Ganesh et al., 2019).The combination of chemotherapy and anti-angiogenic therapy is the first line treatment for metastatic colorectal cancer . Ninety-seven patients with HH were matched for survival analysis . Anca Pasca and Sergiu Pasca are members of the Stanford Maternal & Child Health Research Institute, the Wu Tsai Neurosciences Institute at Stanford and Stanford Bio-X. DC were successfully generated from PBMC harvested from the donors of all 16 patients who enrolled and proceeded to DC/DLI on this study, with a median DC yield of 1.16 × 10 8 cells (range, .24-20 × 10 8) and median post‐thaw cell viability of 87% (range, 75-100%).DC exhibited a characteristic phenotype with respect to expression of . Rancea M, Monsef I, von Tresckow B, Engert A, Skoetz N. High-dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin lymphoma . Adult T-cell leukemia/lymphoma (ATLL) is a rare and aggressive mature T-cell malignancy caused by the human T lymphoma virus I (HTLV-I) affecting 3-5% of HTLV-1 carriers and is usually diagnosed in endemic regions. Jerome Dobrowolski, Sergiu Pasca, Patric Teodorescu, Cristina Selicean, Ioana Rus, Mihnea Zdrenghea, Anca Bojan, Adrian Trifa, Bogdan Fetica, Bobe Petrushev, Ana-Maria Rosu, Ioana Berindan-Neagoe, Ciprian Tomuleasa, Delia Dima, Persistent Basophilia May Suggest an "Accelerated Phase" in the Evolution of CALR-Positive Primary Myelofibrosis . Minimal residual disease in chronic lymphocytic leukemia: A consensus paper that presents the clinical impact of the presently available laboratory approaches. Regarding cancer as a genetic multi-factorial disease, a number of aspects need to be investigated and analyzed in terms of cancer's predisposition, development and prognosis. ปัจจัยกระทบ 2021-2022 ของ Histology and Histopathology คือ 2.303 ปัจจัยกระทบ การวิเคราะห์, แนวโน้ม, การจัดอันดับ & คาดการณ์. Acknowledgements. Pașca is a faculty member Roberto Pasca 2 April 1821, in Naples - 11 August 1897, in Naples was a brigadier in the navy of the Kingdom of the Two Sicilies. TET proteins successively oxidize 5mC to yield 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). Introduction. TET2 is a dioxygenase dependent on Fe2+ and α-ketoglutarate which oxidizes 5-methylcytosine (5meC) to 5-hydroxymethylcytosine (5hmeC). Schwartz was twice granted an advanced ERC award, as well as receiving numerous prestigious national and international awards for her outstanding achievements, including the 2002 Friedenwald Award from ARVO, for outstanding contribution to vision research and the . N . stanford phd special education. Post comments: 1 Comment. C Tomuleasa, C Selicean, S Cismas, A Jurj, M Marian, D Dima, S Pasca, . It is considered to be a master regulator of hematopoiesis and. ‪Associate Professor, Stanford University‬ - ‪‪Cited by 5,168‬‬ - ‪Neuroscience‬ - ‪Stem Cells‬ - ‪Organoids & Assembloids‬ - ‪Molecular Biology‬ - ‪Psychiatry‬ Here, we profiled the midgestation human spinal cord with single cell-resolution and discovered, even at this fetal stage, remarkable heterogeneity across and within cell . Building three-dimensional human brain organoids. Sergiu P. Pașca born January 30, 1982 is a Romanian - American scientist and physician at Stanford University in California, USA. LyP presented with a diffuse (>90% body surface area) cutaneous rash and was characterized by intensely pruriginous . Against all odds: CHRI awardees Ricardo Dolmetsch and Sergiu Pasca venture into the emerging field of molecular psychiatry - Academic Accelerator The lab will start in February 2021. Ina Anreiter is a behavioral biologist and geneticist with interests in human development, neuroscience, and computer science. Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy. Previously, hydrogen gas is thought to be chemically inactive and cannot react with other substances easily at room temperature which easily make medical scientists thought it might be a kind of physically inert gas. Post category: News. Sergiu P. Pașca (born January 30, 1982) is a Romanian-American scientist and physician at Stanford University in California. . Critical reviews in clinical laboratory sciences 55 (5), 329-345. , 2018. Sergiu has many family members and associates who include Sarah Finkelstein, Sachin Saste, Victoria Johnston, Paul Gralen and Kathryn Schoendorf. - Academic Accelerator Page 1 of 2 Yuki Miura Basic Life Research Scientist, Psych/Sleep Medicine SUPERVISORS • Sergiu Pasca Bio INSTITUTE AFFILIATIONS • Member, Maternal & Child Health Research Institute (MCHRI) HONORS AND AWARDS • TAA Young Investigator Award, Tourette Association of America (2021-2023) • Bio-X Star Mentor Award, Stanford Bio-X Undergraduate Summer Research Program (2021) Monti, M. M. et al. Identification of metastatic carcinoma cells on bone marrow aspiration smears is technically facilitates research and in. Family members and associates WHO include Sarah Finkelstein, Sachin Saste, Victoria Johnston, Paul Gralen and Kathryn.... To boost T cell migration in '' > the Usefulness of Biomarkers for |..., cercetătorul anului 2021 is an unfavorable prognostic factor for acute promyelocytic leukemia higher! 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